Henry Vanbrocklin, PhD

Title(s)Professor, Radiology
SchoolSchool of Medicine
Address185 Berry Street Bldg B, #165
San Francisco CA 94158
Phone415-353-4569
ORCID ORCID Icon0000-0003-2849-0841 Additional info
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    Collapse Biography 
    Collapse Awards and Honors
    RPSC, SNMMI2020Michael J. Welch Award
    UCSF MSBI Program2019MSBI Outstanding Teacher Award
    SNMMI2018Fellow, Society of Nuclear Medicine and Molecular Imaging
    Acad Radiol & Biomed Imag Res2018Distinguished Investigator
    Molecular Imaging 2011Editor-in-Chief
    Society of Nuclear Medicine2010SNM Presidents Distinguished Service Award
    US Department of Energy1990  - 1992Alexander Hollaender Distinguished Postdoctoral Fellow

    Collapse Overview 
    Collapse Overview
    Henry VanBrocklin, PhD, is a Professor in Residence, Director of the Radiopharmaceutical Research Program in the Center for Molecular and Functional Imaging (CMFI) at the University of California, San Francisco China Basin, and he is a Joint Faculty Scientist at the Lawrence Berkeley National Laboratory. Dr. VanBrocklin obtained his PhD in Radiopharmaceutical Chemistry from Washington University, St. Louis in 1990, and he completed a two-year postdoctoral program at the University of Illinois, Urbana in 1992. He maintains an active radiotracer research program in addition to providing tracers for collaborative basic science and translational clinical research. His research interests include short-lived radioisotope production to the creation of fluorine-18 and carcbon-11 labeling chemistry strategies for new radiotracer preparations and applications.

    Dr. VanBrocklin is one of the core faculty for the Master's in Biomedical Imaging (MSBI) program and a member of the MSBI executive committee.

    Dr. VanBrocklin was awarded the Alexander Hollaender Distinguished Postdoctoral Fellowship from the U.S. Department of Energy for developing positron-labeled estrogens, progestins, and androgens for tumor imaging. He has 70 published research articles.

    Expertise:
    Radiopharmaceutical

    Specialty:
    Short-lived radioisotope production to the creation of fluorine-18 and carbon-11 labeling chemistry strategies for new radiotracer preparations and applications, development of positron-labeled estrogens, progestin’s, androgens for tumor imaging

    Professional Interests:
    Developing radiopharmaceutical probes for PET and SPECT imaging applications including tracers for blood flow measurement, receptor-targeted tracers for prostate, pancreatic and breast cancer, and neurological imaging agents for neuroinflammation and excititory amino acid transport.

    Education and Training:
    • Doctor of Philosophy: Washington University, St. Louis - Radiopharmaceutical Chemistry
    • Postdoctoral Fellow: University of Illinois, Urbana

    Collapse Research 
    Collapse Research Activities and Funding
    Molecular Imaging of persistent HIV: CD30
    NIH R21AI152936Jan 12, 2021 - Dec 31, 2022
    Role: Principal Investigator
    In Vivo PET Imaging of HIV Infection
    NIH R01AI152932Aug 12, 2020 - Jul 31, 2025
    Role: Co-Principal Investigator
    Improving availability of ImmunoPET via automation of radio-synthesis and quality control of antibody-based cancer imaging PET tracers on a single platform.
    NIH R43CA235909Sep 18, 2019 - Aug 31, 2020
    Role: Co-Principal Investigator
    Astroglial EAAT2 Changes in Live TBI Brain Determined by PET Imaging
    NIH R41NS105309Sep 1, 2018 - Dec 31, 2020
    Role: Principal Investigator
    Mitigation of quality and compliance risks in radio-pharmaceutical production by implementation of an automated release testing technology.
    NIH U01FD005517Sep 15, 2015 - Aug 31, 2021
    Role: Co-Principal Investigator
    Molecular Imaging of Chemical Threats and Countermeasures
    NIH U01NS092495Aug 1, 2015 - Jul 31, 2021
    Role: Co-Principal Investigator
    In vivo reporters of gene expression
    NIH R21AI114283Jul 15, 2014 - Apr 30, 2018
    Role: Co-Principal Investigator
    PET and MR-Compatible Bioreactor for Cross-Platform Biomarker Development
    NIH R21CA171766Aug 1, 2012 - Jul 31, 2015
    Role: Principal Investigator
    In Vivo Pharmacokinetic and Pharmacodynamic Dispositions of Positron Radiolabeled
    NIH R21NS072079Sep 30, 2010 - Aug 31, 2013
    Role: Co-Principal Investigator
    MicroPET/CT for Small Animal Imaging
    NIH S10RR023051Jun 1, 2007 - May 31, 2009
    Role: Principal Investigator
    Evaluation of Iodorotenone, A SPECT Perfusion Tracer
    NIH R01EB000482Mar 10, 2003 - Feb 29, 2008
    Role: Principal Investigator
    Targeted Molecular Probes for Tumor Imaging
    NIH R01CA094253Sep 5, 2002 - Aug 31, 2008
    Role: Principal Investigator
    DEVELOPMENT OF CANCER IMAGING AGENTS
    NIH R21CA079823Feb 1, 1999 - Jan 31, 2001
    Role: Principal Investigator
    MYOCARDIAL FLOW, FUNCTION AND METABOLISM BY PET AND MRI
    NIH P01HL025840Aug 1, 1980 - Aug 30, 2002
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Development of CD46 targeted alpha theranostics in prostate cancer using 134Ce/225Ac-Macropa-PEG4-YS5. Theranostics. 2024; 14(4):1344-1360. Bobba KN, Bidkar AP, Wadhwa A, Meher N, Drona S, Sorlin AM, Bidlingmaier S, Zhang L, Wilson DM, Chan E, Greenland NY, Aggarwal R, VanBrocklin HF, He J, Chou J, Seo Y, Liu B, Flavell RR. PMID: 38389832; PMCID: PMC10879874.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. [11C]Paraoxon: Radiosynthesis, Biodistribution and In Vivo Positron Emission Tomography Imaging in Rat. J Pharmacol Exp Ther. 2024 01 17; 388(2):333-346. Hayes TR, Chao CK, Blecha JE, Huynh TL, VanBrocklin HF, Zinn KR, Gerdes JM, Thompson CM. PMID: 37770203; PMCID: PMC10801775.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    3. CD46-targeted theranostics for Positron Emission Tomography and 225Ac-Radiopharmaceutical Therapy of Multiple Myeloma. Clin Cancer Res. 2023 Dec 18. Wadhwa A, Wang S, Patiño-Escobar B, Bidkar AP, Bobba KN, Chan E, Meher N, Bidlingmaier S, Su Y, Dhrona S, Geng H, Sarin V, VanBrocklin HF, Wilson DM, He J, Zhang L, Steri V, Wong SW, Martin TG, Seo Y, Liu B, Wiita AP, Flavell RR. PMID: 38109209.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Nat Immunol. 2023 Oct; 24(10):1778. Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. PMID: 37723351.
      View in: PubMed   Mentions:    Fields:    
    5. SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC). Nat Immunol. 2023 10; 24(10):1616-1627. Proal AD, VanElzakker MB, Aleman S, Bach K, Boribong BP, Buggert M, Cherry S, Chertow DS, Davies HE, Dupont CL, Deeks SG, Eimer W, Ely EW, Fasano A, Freire M, Geng LN, Griffin DE, Henrich TJ, Iwasaki A, Izquierdo-Garcia D, Locci M, Mehandru S, Painter MM, Peluso MJ, Pretorius E, Price DA, Putrino D, Scheuermann RH, Tan GS, Tanzi RE, VanBrocklin HF, Yonker LM, Wherry EJ. PMID: 37667052.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    6. Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19. medRxiv. 2023 Jul 31. Peluso MJ, Ryder D, Flavell R, Wang Y, Levi J, LaFranchi BH, Deveau TM, Buck AM, Munter SE, Asare KA, Aslam M, Koch W, Szabo G, Hoh R, Deswal M, Rodriguez A, Buitrago M, Tai V, Shrestha U, Lu S, Goldberg SA, Dalhuisen T, Durstenfeld MS, Hsue PY, Kelly JD, Kumar N, Martin JN, Gambir A, Somsouk M, Seo Y, Deeks SG, Laszik ZG, VanBrocklin HF, Henrich TJ. PMID: 37577714; PMCID: PMC10418298.
      View in: PubMed   Mentions:
    7. Evaluation of 134Ce/134La as a PET Imaging Theranostic Pair for 225Ac α-Radiotherapeutics. J Nucl Med. 2023 07; 64(7):1076-1082. Bobba KN, Bidkar AP, Meher N, Fong C, Wadhwa A, Dhrona S, Sorlin A, Bidlingmaier S, Shuere B, He J, Wilson DM, Liu B, Seo Y, VanBrocklin HF, Flavell RR. PMID: 37201957; PMCID: PMC10315697.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    8. Treatment of Prostate Cancer with CD46-targeted 225Ac Alpha Particle Radioimmunotherapy. Clin Cancer Res. 2023 05 15; 29(10):1916-1928. Bidkar AP, Wang S, Bobba KN, Chan E, Bidlingmaier S, Egusa EA, Peter R, Ali U, Meher N, Wadhwa A, Dhrona S, Dasari C, Beckford-Vera D, Su Y, Tang R, Zhang L, He J, Wilson DM, Aggarwal R, VanBrocklin HF, Seo Y, Chou J, Liu B, Flavell RR. PMID: 36917693; PMCID: PMC10183825.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    9. A feasibility study for quantitative assessment of cerebrovascular malformations using flutriciclamide ([18F]GE-180) PET/MRI. Front Med (Lausanne). 2023; 10:1091463. Kim SJW, Lupo JM, Chen Y, Pampaloni MH, VanBrocklin HF, Narvid J, Kim H, Seo Y. PMID: 37089589; PMCID: PMC10116613.
      View in: PubMed   Mentions:
    10. Organ-specific fuel rewiring in acute and chronic hypoxia redistributes glucose and fatty acid metabolism. Cell Metab. 2023 03 07; 35(3):504-516.e5. Midha AD, Zhou Y, Queliconi BB, Barrios AM, Haribowo AG, Chew BTL, Fong COY, Blecha JE, VanBrocklin H, Seo Y, Jain IH. PMID: 36889284; PMCID: PMC10077660.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    11. PSMA-Targeted Nanotheranostics for Imaging and Radiotherapy of Prostate Cancer. Pharmaceuticals (Basel). 2023 Feb 17; 16(2). Meher N, VanBrocklin HF, Wilson DM, Flavell RR. PMID: 37259457; PMCID: PMC9964110.
      View in: PubMed   Mentions: 3  
    12. Prostate-Specific Membrane Antigen Targeted Deep Tumor Penetration of Polymer Nanocarriers. ACS Appl Mater Interfaces. 2022 Nov 16; 14(45):50569-50582. Meher N, Ashley GW, Bidkar AP, Dhrona S, Fong C, Fontaine SD, Beckford Vera DR, Wilson DM, Seo Y, Santi DV, VanBrocklin HF, Flavell RR. PMID: 36318757; PMCID: PMC9673064.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    13. Biodistribution of a Mitochondrial Metabolic Tracer, [18F]F-AraG, in Healthy Volunteers. Mol Imaging. 2022; 2022:3667417. Levi J, Duan H, Yaghoubi S, Packiasamy J, Huynh L, Lam T, Shaikh F, Behera D, Song H, Blecha J, Jivan S, Seo Y, VanBrocklin HF. PMID: 36072652; PMCID: PMC9400547.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Imaging joint infections using D-methyl-11C-methionine PET/MRI: initial experience in humans. Eur J Nucl Med Mol Imaging. 2022 09; 49(11):3761-3771. Polvoy I, Seo Y, Parker M, Stewart M, Siddiqua K, Manacsa HS, Ravanfar V, Blecha J, Hope TA, Vanbrocklin H, Flavell RR, Barry J, Hansen E, Villanueva-Meyer JE, Engel J, Rosenberg OS, Wilson DM, Ohliger MA. PMID: 35732972; PMCID: PMC9399217.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    15. Evaluating Radioactive Analogs of Doxorubicin to Quantify ChemoFilter Binding and Whole-Body Positron Emission Tomography/Magnetic Resonance Imaging for Drug Biodistribution. J Vasc Interv Radiol. 2022 06; 33(6):687-694. Kumar P, Yee C, Blecha JE, Hayes TR, Kilbride BF, Stillson C, Losey AD, Mastria E, Jordan CD, Huynh TL, Moore T, Wilson MW, VanBrocklin HF, Hetts SW. PMID: 35301127; PMCID: PMC9156544.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    16. First-in-human immunoPET imaging of HIV-1 infection using 89Zr-labeled VRC01 broadly neutralizing antibody. Nat Commun. 2022 03 09; 13(1):1219. Beckford-Vera DR, Flavell RR, Seo Y, Martinez-Ortiz E, Aslam M, Thanh C, Fehrman E, Pardons M, Kumar S, Deitchman AN, Ravanfar V, Schulte B, Wu IK, Pan T, Reeves JD, Nixon CC, Iyer NS, Torres L, Munter SE, Hyunh T, Petropoulos CJ, Hoh R, Franc BL, Gama L, Koup RA, Mascola JR, Chomont N, Deeks SG, VanBrocklin HF, Henrich TJ. PMID: 35264559; PMCID: PMC8907355.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    17. Proceedings: PET Drugs-A Workshop on Inspections Management and Regulatory Considerations. J Nucl Med. 2022 07; 63(7):1117-1123. Bunning S, Ignace C, Mattmuller S, Schwarz SW, Scott PJH, VanBrocklin HF, Zigler SS, Coalition of Drug Manufacturers. PMID: 35058318; PMCID: PMC9258562.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen. ACS Appl Mater Interfaces. 2021 Nov 24; 13(46):54739-54752. Meher N, Seo K, Wang S, Bidkar AP, Fogarty M, Dhrona S, Huang X, Tang R, Blaha C, Evans MJ, Raleigh DR, Jun YW, VanBrocklin HF, Desai TA, Wilson DM, Ozawa T, Flavell RR. PMID: 34752058.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    19. Longitudinal Imaging of T Cells and Inflammatory Demyelination in a Preclinical Model of Multiple Sclerosis Using 18F-FAraG PET and MRI. J Nucl Med. 2022 01; 63(1):140-146. Guglielmetti C, Levi J, Huynh TL, Tiret B, Blecha J, Tang R, VanBrocklin H, Chaumeil MM. PMID: 33837066; PMCID: PMC8717198.
      View in: PubMed   Mentions: 7     Fields:    
    20. Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats. Chem Res Toxicol. 2021 01 18; 34(1):63-69. Hayes TR, Chao CK, Blecha JE, Huynh TL, Zinn KR, Thompson CM, Gerdes JM, VanBrocklin HF. PMID: 33373198; PMCID: PMC7818893.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    21. Total-Body PET Imaging in Infectious Diseases. PET Clin. 2021 Jan; 16(1):89-97. Henrich TJ, Jones T, Beckford-Vera D, Price PM, VanBrocklin HF. PMID: 33160926; PMCID: PMC10270309.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. Positron Emission Tomography Imaging of Functional Transforming Growth Factor β (TGFβ) Activity and Benefit of TGFβ Inhibition in Irradiated Intracranial Tumors. Int J Radiat Oncol Biol Phys. 2021 02 01; 109(2):527-539. Gonzalez-Junca A, Reiners O, Borrero-Garcia LD, Beckford-Vera D, Lazar AA, Chou W, Braunstein S, VanBrocklin H, Franc BL, Barcellos-Hoff MH. PMID: 33007434; PMCID: PMC7856163.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    23. The Synthesis and Structural Requirements for Measuring Glucocorticoid Receptor Expression In Vivo with (±)-11C-YJH08 PET. J Nucl Med. 2021 05 10; 62(5):723-731. Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Parker MFL, Blecha JE, Drake CR, VanBrocklin HF, Garrido-Ruiz D, Jacobson MP, Aggarwal R, Behr SC, Flavell RR, Wilson DM, Seo Y, Evans MJ. PMID: 32887758; PMCID: PMC8844266.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    24. An Analysis of Isoclonal Antibody Formats Suggests a Role for Measuring PD-L1 with Low Molecular Weight PET Radiotracers. Mol Imaging Biol. 2020 12; 22(6):1553-1561. Wei J, Wang YH, Lee CY, Truillet C, Oh DY, Xu Y, Ruggero D, Flavell RR, VanBrocklin HF, Seo Y, Craik CS, Fong L, Wang CI, Evans MJ. PMID: 32813112; PMCID: PMC7669684.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    25. Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[18 F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [18 F]-VXS. Ann N Y Acad Sci. 2020 11; 1479(1):180-195. Hayes TR, Blecha JE, Chao CK, Huynh TL, VanBrocklin HF, Zinn KR, Taylor PW, Gerdes JM, Thompson CM. PMID: 32436233; PMCID: PMC7677195.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    26. 124I-MIBG PET/CT to Monitor Metastatic Disease in Children with Relapsed Neuroblastoma. J Nucl Med. 2021 01; 62(1):43-47. Aboian MS, Huang SY, Hernandez-Pampaloni M, Hawkins RA, VanBrocklin HF, Huh Y, Vo KT, Gustafson WC, Matthay KK, Seo Y. PMID: 32414950; PMCID: PMC9364877.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    27. A Novel Radioligand Reveals Tissue Specific Pharmacological Modulation of Glucocorticoid Receptor Expression with Positron Emission Tomography. ACS Chem Biol. 2020 06 19; 15(6):1381-1391. Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Blecha JE, VanBrocklin HF, Seo Y, Sayeed M, Feldman BJ, Aggarwal R, Behr SC, Shao H, Wilson DM, Villanueva-Meyer JE, Gestwicki JE, Evans MJ. PMID: 32255605; PMCID: PMC8031368.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    28. Arabinofuranose-derived positron-emission tomography radiotracers for detection of pathogenic microorganisms. J Labelled Comp Radiopharm. 2020 05 15; 63(5):231-239. Kalita M, Parker MFL, Luu JM, Stewart MN, Blecha JE, VanBrocklin HF, Evans MJ, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 32222086; PMCID: PMC7364301.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    29. PET/CT Imaging of Human TNFα Using [89Zr]Certolizumab Pegol in a Transgenic Preclinical Model of Rheumatoid Arthritis. Mol Imaging Biol. 2020 02; 22(1):105-114. Beckford-Vera DR, Gonzalez-Junca A, Janneck JS, Huynh TL, Blecha JE, Seo Y, Li X, VanBrocklin HF, Franc BL. PMID: 31065895.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    30. High Enantiomeric Excess In-Loop Synthesis of d-[methyl-11C]Methionine for Use as a Diagnostic Positron Emission Tomography Radiotracer in Bacterial Infection. ACS Infect Dis. 2020 01 10; 6(1):43-49. Stewart MN, Parker MFL, Jivan S, Luu JM, Huynh TL, Schulte B, Seo Y, Blecha JE, Villanueva-Meyer JE, Flavell RR, VanBrocklin HF, Ohliger MA, Rosenberg O, Wilson DM. PMID: 31697062; PMCID: PMC7364312.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    31. PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89. Mol Cancer Ther. 2020 02; 19(2):673-679. Beckford Vera DR, Fontaine SD, VanBrocklin HF, Hearn BR, Reid R, Ashley GW, Santi DV. PMID: 31744896.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    32. Seeing Is Believing: Nuclear Imaging of HIV Persistence. Front Immunol. 2019; 10:2077. Henrich TJ, Hsue PY, VanBrocklin H. PMID: 31572355; PMCID: PMC6751256.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    33. Synthesis and Initial Biological Evaluation of Boron-Containing Prostate-Specific Membrane Antigen Ligands for Treatment of Prostate Cancer Using Boron Neutron Capture Therapy. Mol Pharm. 2019 09 03; 16(9):3831-3841. Wang S, Blaha C, Santos R, Huynh T, Hayes TR, Beckford-Vera DR, Blecha JE, Hong AS, Fogarty M, Hope TA, Raleigh DR, Wilson DM, Evans MJ, VanBrocklin HF, Ozawa T, Flavell RR. PMID: 31381351; PMCID: PMC6722010.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    34. Divergent synthesis of organophosphate [11C]VX- and [11C]Sarin-surrogates from a common set of starting materials. Appl Radiat Isot. 2019 Sep; 151:182-186. Hayes TR, Blecha JE, Thompson CM, Gerdes JM, VanBrocklin HF. PMID: 31202183; PMCID: PMC6688906.
      View in: PubMed   Mentions: 2     Fields:    
    35. Imaging of Activated T Cells as an Early Predictor of Immune Response to Anti-PD-1 Therapy. Cancer Res. 2019 07 01; 79(13):3455-3465. Levi J, Lam T, Goth SR, Yaghoubi S, Bates J, Ren G, Jivan S, Huynh TL, Blecha JE, Khattri R, Schmidt KF, Jennings D, VanBrocklin H. PMID: 31064845; PMCID: PMC6606349.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    36. Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures. Neurobiol Dis. 2020 01; 133:104455. Thompson CM, Gerdes JM, VanBrocklin HF. PMID: 31022458; PMCID: PMC6810781.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    37. Enzymatically Catalyzed Radiofluorination of Biomolecules. Methods Mol Biol. 2019; 2033:191-205. Drake CR, Evans MJ, VanBrocklin HF. PMID: 31332755.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    38. Phase I Study of CTT1057, an 18F-Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate-Specific Membrane Antigen in Prostate Cancer. J Nucl Med. 2019 07; 60(7):910-916. Behr SC, Aggarwal R, VanBrocklin HF, Flavell RR, Gao K, Small EJ, Blecha J, Jivan S, Hope TA, Simko JP, Kurhanewicz J, Noworolski SM, Korn NJ, De Los Santos R, Cooperberg MR, Carroll PR, Nguyen HG, Greene KL, Langton-Webster B, Berkman CE, Seo Y. PMID: 30464040; PMCID: PMC6604687.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    39. Radiosynthesis of O-(1-[18 F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: A novel PET tracer surrogate of sarin. J Labelled Comp Radiopharm. 2018 12; 61(14):1089-1094. Hayes TR, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF. PMID: 30347484; PMCID: PMC6661111.
      View in: PubMed   Mentions: 4     Fields:    
    40. A Patient-derived Xenograft Model of Pancreatic Neuroendocrine Tumors Identifies Sapanisertib as a Possible New Treatment for Everolimus-resistant Tumors. Mol Cancer Ther. 2018 12; 17(12):2702-2709. Chamberlain CE, German MS, Yang K, Wang J, VanBrocklin H, Regan M, Shokat KM, Ducker GS, Kim GE, Hann B, Donner DB, Warren RS, Venook AP, Bergsland EK, Lee D, Wang Y, Nakakura EK. PMID: 30254185; PMCID: PMC6279485.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    41. Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [11C]2-Pyridinealdoxime Methiodide ([11C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication. ACS Chem Neurosci. 2018 12 19; 9(12):3007-3014. Neumann KD, Blecha JE, Hayes TR, Huynh T, Chao CK, Guilloteau N, Zinn KR, VanBrocklin HF, Thompson CM, Gerdes JM. PMID: 30071719; PMCID: PMC6699170.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    42. Late-stage deuteration of 13C-enriched substrates for T1 prolongation in hyperpolarized 13C MRI. Chem Commun (Camb). 2018 May 17; 54(41):5233-5236. Taglang C, Korenchan DE, von Morze C, Yu J, Najac C, Wang S, Blecha JE, Subramaniam S, Bok R, VanBrocklin HF, Vigneron DB, Ronen SM, Sriram R, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 29726563; PMCID: PMC6054790.
      View in: PubMed   Mentions: 16     Fields:    
    43. Quantification of 89 Zr-Iron oxide nanoparticle biodistribution using PET-MR and ultrashort TE sequences. J Magn Reson Imaging. 2018 12; 48(6):1717-1720. Jordan CD, Han M, Kondapavulur S, Vera DB, Neumann KD, Moore T, Stillson C, Krug R, Behr S, Seo Y, VanBrocklin HF, Larson PEZ, Wilson M, Martin AJ, Hetts SW. PMID: 29761624; PMCID: PMC6235733.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    44. [11C]Para-Aminobenzoic Acid: A Positron Emission Tomography Tracer Targeting Bacteria-Specific Metabolism. ACS Infect Dis. 2018 07 13; 4(7):1067-1072. Mutch CA, Ordonez AA, Qin H, Parker M, Bambarger LE, Villanueva-Meyer JE, Blecha J, Carroll V, Taglang C, Flavell R, Sriram R, VanBrocklin H, Rosenberg O, Ohliger MA, Jain SK, Neumann KD, Wilson DM. PMID: 29712422; PMCID: PMC6045447.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    45. Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers. Sci Rep. 2017 08 11; 7(1):7903. Neumann KD, Villanueva-Meyer JE, Mutch CA, Flavell RR, Blecha JE, Kwak T, Sriram R, VanBrocklin HF, Rosenberg OS, Ohliger MA, Wilson DM. PMID: 28801560; PMCID: PMC5554133.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    46. A PET Imaging Strategy to Visualize Activated T Cells in Acute Graft-versus-Host Disease Elicited by Allogenic Hematopoietic Cell Transplant. Cancer Res. 2017 06 01; 77(11):2893-2902. Ronald JA, Kim BS, Gowrishankar G, Namavari M, Alam IS, D'Souza A, Nishikii H, Chuang HY, Ilovich O, Lin CF, Reeves R, Shuhendler A, Hoehne A, Chan CT, Baker J, Yaghoubi SS, VanBrocklin HF, Hawkins R, Franc BL, Jivan S, Slater JB, Verdin EF, Gao KT, Benjamin J, Negrin R, Gambhir SS. PMID: 28572504; PMCID: PMC5505323.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    47. An improved radiosynthesis of O-(2-[18 F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate: A first-in-class cholinesterase PET tracer. J Labelled Comp Radiopharm. 2017 06 15; 60(7):337-342. Neumann KD, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF. PMID: 28406525; PMCID: PMC6031433.
      View in: PubMed   Mentions: 6     Fields:    
    48. An updated synthesis of [11 C]carfentanil for positron emission tomography (PET) imaging of the μ-opioid receptor. J Labelled Comp Radiopharm. 2017 06 30; 60(8):375-380. Blecha JE, Henderson BD, Hockley BG, VanBrocklin HF, Zubieta JK, DaSilva AF, Kilbourn MR, Koeppe RA, Scott PJH, Shao X. PMID: 28419528; PMCID: PMC9886010.
      View in: PubMed   Mentions: 6     Fields:    
    49. Dicarboxylic acids as pH sensors for hyperpolarized 13C magnetic resonance spectroscopic imaging. Analyst. 2017 May 02; 142(9):1429-1433. Korenchan DE, Taglang C, von Morze C, Blecha JE, Gordon JW, Sriram R, Larson PEZ, Vigneron DB, VanBrocklin HF, Kurhanewicz J, Wilson DM, Flavell RR. PMID: 28322385; PMCID: PMC5462110.
      View in: PubMed   Mentions: 12     Fields:    
    50. 11C-L-methyl methionine dynamic PET/CT of skeletal muscle: response to protein supplementation compared to L-[ring 13C6] phenylalanine infusion with serial muscle biopsy. Ann Nucl Med. 2017 May; 31(4):295-303. Arentson-Lantz EJ, Saeed IH, Frassetto LA, Masharani U, Harnish RJ, Seo Y, VanBrocklin HF, Hawkins RA, Mari-Aparici C, Pampaloni MH, Slater J, Paddon-Jones D, Lang TF. PMID: 28260185; PMCID: PMC5397459.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. In Vivo PET Imaging of the Activated Immune Environment in a Small Animal Model of Inflammatory Arthritis. Mol Imaging. 2017 01 01; 16:1536012117712638. Franc BL, Goth S, MacKenzie J, Li X, Blecha J, Lam T, Jivan S, Hawkins RA, VanBrocklin H. PMID: 28625080; PMCID: PMC5480631.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    52. Optimization of an endovascular magnetic filter for maximized capture of magnetic nanoparticles. Biomed Microdevices. 2016 12; 18(6):109. Kondapavulur S, Cote AM, Neumann KD, Jordan CD, McCoy D, Mabray MC, Liu D, Sze CH, Gautam A, VanBrocklin HF, Wilson M, Hetts SW. PMID: 27830455; PMCID: PMC5468174.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    53. Structure-Activity Relationship of (18)F-Labeled Phosphoramidate Peptidomimetic Prostate-Specific Membrane Antigen (PSMA)-Targeted Inhibitor Analogues for PET Imaging of Prostate Cancer. J Med Chem. 2016 06 23; 59(12):5684-94. Dannoon S, Ganguly T, Cahaya H, Geruntho JJ, Galliher MS, Beyer SK, Choy CJ, Hopkins MR, Regan M, Blecha JE, Skultetyova L, Drake CR, Jivan S, Barinka C, Jones EF, Berkman CE, VanBrocklin HF. PMID: 27228467; PMCID: PMC6016545.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    54. [(11)C]acetate PET Imaging is not Always Associated with Increased Lipogenesis in Hepatocellular Carcinoma in Mice. Mol Imaging Biol. 2016 06; 18(3):360-7. Li L, Che L, Wang C, Blecha JE, Li X, VanBrocklin HF, Calvisi DF, Puchowicz M, Chen X, Seo Y. PMID: 26567114; PMCID: PMC4866912.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    55. Ictal lack of binding to brain parenchyma suggests integrity of the blood-brain barrier for 11C-dihydroergotamine during glyceryl trinitrate-induced migraine. Brain. 2016 07; 139(Pt 7):1994-2001. Schankin CJ, Maniyar FH, Seo Y, Kori S, Eller M, Chou DE, Blecha J, Murphy ST, Hawkins RA, Sprenger T, VanBrocklin HF, Goadsby PJ. PMID: 27234268; PMCID: PMC4939703.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    56. Site-Specific Radiofluorination of Biomolecules with 8-[(18)F]-Fluorooctanoic Acid Catalyzed by Lipoic Acid Ligase. ACS Chem Biol. 2016 06 17; 11(6):1587-94. Drake CR, Sevillano N, Truillet C, Craik CS, VanBrocklin HF, Evans MJ. PMID: 27008570; PMCID: PMC5712215.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    57. [(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography. Chem Commun (Camb). 2016 Apr 07; 52(27):4888-90. Carroll VN, Truillet C, Shen B, Flavell RR, Shao X, Evans MJ, VanBrocklin HF, Scott PJ, Chin FT, Wilson DM. PMID: 26963495; PMCID: PMC4854297.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    58. Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging. Chem Commun (Camb). 2016 Feb 18; 52(14):3030-3. Korenchan DE, Flavell RR, Baligand C, Sriram R, Neumann K, Sukumar S, VanBrocklin H, Vigneron DB, Wilson DM, Kurhanewicz J. PMID: 26792559; PMCID: PMC4864526.
      View in: PubMed   Mentions: 20     Fields:    
    59. Caged [(18)F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography. Bioconjug Chem. 2016 Jan 20; 27(1):170-8. Flavell RR, Truillet C, Regan MK, Ganguly T, Blecha JE, Kurhanewicz J, VanBrocklin HF, Keshari KR, Chang CJ, Evans MJ, Wilson DM. PMID: 26649808; PMCID: PMC4854293.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    60. Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography. Nat Commun. 2015 Oct 01; 6:8448. Page MJ, Lourenço AL, David T, LeBeau AM, Cattaruzza F, Castro HC, VanBrocklin HF, Coughlin SR, Craik CS. PMID: 26423607; PMCID: PMC4593073.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    61. Simultaneous (68)Ga-DOTA-TOC PET/MRI with gadoxetate disodium in patients with neuroendocrine tumor. Abdom Imaging. 2015 Aug; 40(6):1432-40. Hope TA, Pampaloni MH, Nakakura E, VanBrocklin H, Slater J, Jivan S, Aparici CM, Yee J, Bergsland E. PMID: 25820755.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    62. Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor. Prostate. 2015 Oct; 75(14):1601-9. Keshari KR, Wilson DM, Van Criekinge M, Sriram R, Koelsch BL, Wang ZJ, VanBrocklin HF, Peehl DM, O'Brien T, Sampath D, Carano RA, Kurhanewicz J. PMID: 26177608; PMCID: PMC4537380.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    63. A high-affinity [(18)F]-labeled phosphoramidate peptidomimetic PSMA-targeted inhibitor for PET imaging of prostate cancer. Nucl Med Biol. 2015 Oct; 42(10):780-7. Ganguly T, Dannoon S, Hopkins MR, Murphy S, Cahaya H, Blecha JE, Jivan S, Drake CR, Barinka C, Jones EF, VanBrocklin HF, Berkman CE. PMID: 26169882; PMCID: PMC4624265.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    64. Somatostatin imaging of neuroendocrine-differentiated prostate cancer. Clin Nucl Med. 2015 Jun; 40(6):540-1. Hope TA, Aggarwal R, Simko JP, VanBrocklin HF, Ryan CJ. PMID: 25783510.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    65. Synthesis and evaluation of constrained phosphoramidate inhibitors of prostate-specific membrane antigen. Bioorg Med Chem Lett. 2015 Jun 15; 25(12):2536-9. Ley CR, Beattie NR, Dannoon S, Regan M, VanBrocklin H, Berkman CE. PMID: 25956413; PMCID: PMC7588815.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    66. Imaging active urokinase plasminogen activator in prostate cancer. Cancer Res. 2015 Apr 01; 75(7):1225-35. LeBeau AM, Sevillano N, Markham K, Winter MB, Murphy ST, Hostetter DR, West J, Lowman H, Craik CS, VanBrocklin HF. PMID: 25672980; PMCID: PMC4383704.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    67. A boronate-caged [¹⁸F]FLT probe for hydrogen peroxide detection using positron emission tomography. J Am Chem Soc. 2014 Oct 22; 136(42):14742-5. Carroll V, Michel BW, Blecha J, VanBrocklin H, Keshari K, Wilson D, Chang CJ. PMID: 25310369; PMCID: PMC4210116.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    68. Regulatory Requirements for PET Drug Production. J Nucl Med. 2014 Jul; 55(7):1132-7. Schwarz SW, Dick D, VanBrocklin HF, Hoffman JM. PMID: 24914057.
      View in: PubMed   Mentions: 10     Fields:    
    69. A novel fluorine-18 β-fluoroethoxy organophosphate positron emission tomography imaging tracer targeted to central nervous system acetylcholinesterase. ACS Chem Neurosci. 2014 Jul 16; 5(7):519-24. James SL, Ahmed SK, Murphy S, Braden MR, Belabassi Y, VanBrocklin HF, Thompson CM, Gerdes JM. PMID: 24716794; PMCID: PMC4102964.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    70. Imaging the urokinase plasminongen activator receptor in preclinical breast cancer models of acquired drug resistance. Theranostics. 2014; 4(3):267-79. LeBeau AM, Sevillano N, King ML, Duriseti S, Murphy ST, Craik CS, Murphy LL, VanBrocklin HF. PMID: 24505235; PMCID: PMC3915090.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    71. Photons across medicine: relating optical and nuclear imaging. Biomed Opt Express. 2013; 4(12):2751-62. Nordstrom R, Cherry S, Azhdarinia A, Sevick-Muraca E, Vanbrocklin H. PMID: 24409377; PMCID: PMC3862159.
      View in: PubMed   Mentions: 2  
    72. Hyperpolarized [1-13C]dehydroascorbate MR spectroscopy in a murine model of prostate cancer: comparison with 18F-FDG PET. J Nucl Med. 2013 Jun; 54(6):922-8. Keshari KR, Sai V, Wang ZJ, Vanbrocklin HF, Kurhanewicz J, Wilson DM. PMID: 23575993; PMCID: PMC3682497.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    73. Targeting uPAR with antagonistic recombinant human antibodies in aggressive breast cancer. Cancer Res. 2013 Apr 01; 73(7):2070-81. LeBeau AM, Duriseti S, Murphy ST, Pepin F, Hann B, Gray JW, VanBrocklin HF, Craik CS. PMID: 23400595; PMCID: PMC3618559.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    74. Imaging a functional tumorigenic biomarker in the transformed epithelium. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):93-8. LeBeau AM, Lee M, Murphy ST, Hann BC, Warren RS, Delos Santos R, Kurhanewicz J, Hanash SM, VanBrocklin HF, Craik CS. PMID: 23248318; PMCID: PMC3538269.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    75. Tumor dosimetry using [124I]m-iodobenzylguanidine microPET/CT for [131I]m-iodobenzylguanidine treatment of neuroblastoma in a murine xenograft model. Mol Imaging Biol. 2012 Dec; 14(6):735-42. Seo Y, Gustafson WC, Dannoon SF, Nekritz EA, Lee CL, Murphy ST, VanBrocklin HF, Hernandez-Pampaloni M, Haas-Kogan DA, Weiss WA, Matthay KK. PMID: 22382618; PMCID: PMC3369020.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    76. Approach to assessing myocardial perfusion in rats using static [13N]-ammonia images and a small-animal PET. Mol Imaging Biol. 2012 Oct; 14(5):541-5. Vaquero JJ, Gao DW, García-Villaba C, Bacharach S, Vanbrocklin H, Fang Q, Desco M, Lee R, Dae M. PMID: 22278106.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    77. In memoriam: Michael John Welch, Ph.D 1939-2012. Mol Imaging Biol. 2012 Aug; 14(4):393-4. McCarthy TJ, Vanbrocklin HF. PMID: 22718105.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    78. The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist. Biochem J. 2012 Apr 01; 443(1):133-44. Wilson KJ, Mill CP, Gallo RM, Cameron EM, VanBrocklin H, Settleman J, Riese DJ. PMID: 22216880; PMCID: PMC3960720.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    79. Accepting the torch. Mol Imaging. 2012 Feb; 11(1):1. VanBrocklin H. PMID: 22418022.
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    80. Myocardial uptake of 7'-(Z)-[(123)I]iodorotenone during vasodilator stress in dogs with critical coronary stenoses. Circ Cardiovasc Imaging. 2011 Nov; 4(6):685-92. Broisat A, Ruiz M, Goodman NC, Hanrahan SM, Reutter BW, Brennan KM, Janabi M, Schaefer S, Watson DD, Beller GA, VanBrocklin HF, Glover DK. PMID: 21917783; PMCID: PMC3587960.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    81. FDA cGMP requirements for PET drugs. J Nucl Med. 2011 May; 52(5):16N. Norenberg JP, Schwarz S, VanBrocklin H. PMID: 21536923.
      View in: PubMed   Mentions: 3     Fields:    
    82. Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas. Cancer Res. 2011 Apr 01; 71(7):2428-32. Iyer AK, Lan X, Zhu X, Su Y, Feng J, Zhang X, Gao D, Seo Y, Vanbrocklin HF, Broaddus VC, Liu B, He J. PMID: 21447742; PMCID: PMC3071798.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    83. Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F]fluoroanilino)quinazolines, potential EGFR imaging probes. Bioorg Med Chem. 2011 May 01; 19(9):2959-65. Vasdev N, Dorff PN, O'Neil JP, Chin FT, Hanrahan S, VanBrocklin HF. PMID: 21478021; PMCID: PMC3099137.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    84. Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems. Clin Cancer Res. 2011 Apr 15; 17(8):2339-49. More SS, Itsara M, Yang X, Geier EG, Tadano MK, Seo Y, Vanbrocklin HF, Weiss WA, Mueller S, Haas-Kogan DA, Dubois SG, Matthay KK, Giacomini KM. PMID: 21421857; PMCID: PMC3247296.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    85. The effect of internalizing human single chain antibody fragment on liposome targeting to epithelioid and sarcomatoid mesothelioma. Biomaterials. 2011 Apr; 32(10):2605-13. Iyer AK, Su Y, Feng J, Lan X, Zhu X, Liu Y, Gao D, Seo Y, Vanbrocklin HF, Courtney Broaddus V, Liu B, He J. PMID: 21255833; PMCID: PMC3040448.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    86. CGMP for PET drugs: important steps to take now. J Nucl Med. 2010 Dec; 51(12):17N. Vanbrocklin H, Schwarz S. PMID: 21098789.
      View in: PubMed   Mentions:    Fields:    
    87. Radiolabeled small molecule protein kinase inhibitors for imaging with PET or SPECT. Molecules. 2010 Nov 15; 15(11):8260-78. Hicks JW, VanBrocklin HF, Wilson AA, Houle S, Vasdev N. PMID: 21079565; PMCID: PMC6259110.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    88. Radiation dose estimation using preclinical imaging with 124I-metaiodobenzylguanidine (MIBG) PET. Med Phys. 2010 Sep; 37(9):4861-7. Lee CL, Wahnishe H, Sayre GA, Cho HM, Kim HJ, Hernandez-Pampaloni M, Hawkins RA, Dannoon SF, VanBrocklin HF, Itsara M, Weiss WA, Yang X, Haas-Kogan DA, Matthay KK, Seo Y. PMID: 20964203; PMCID: PMC2937055.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    89. Targeted in vivo extracellular matrix formation promotes neovascularization in a rodent model of myocardial infarction. PLoS One. 2010 Apr 28; 5(4):e10384. Mihardja SS, Gao D, Sievers RE, Fang Q, Feng J, Wang J, Vanbrocklin HF, Larrick JW, Huang M, Dae M, Lee RJ. PMID: 20442783; PMCID: PMC2860995.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    90. Design of targeted cardiovascular molecular imaging probes. J Nucl Med. 2010 May 01; 51 Suppl 1:3S-17S. Anderson CJ, Bulte JW, Chen K, Chen X, Khaw BA, Shokeen M, Wooley KL, VanBrocklin HF. PMID: 20395345; PMCID: PMC3629978.
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    91. Targeting prostate cancer cells in vivo using a rapidly internalizing novel human single-chain antibody fragment. J Nucl Med. 2010 Mar; 51(3):427-32. He J, Wang Y, Feng J, Zhu X, Lan X, Iyer AK, Zhang N, Seo Y, VanBrocklin HF, Liu B. PMID: 20150269; PMCID: PMC2832590.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    92. Assessment of an 18F-labeled phosphoramidate peptidomimetic as a new prostate-specific membrane antigen-targeted imaging agent for prostate cancer. J Nucl Med. 2009 Dec; 50(12):2042-8. Lapi SE, Wahnishe H, Pham D, Wu LY, Nedrow-Byers JR, Liu T, Vejdani K, VanBrocklin HF, Berkman CE, Jones EF. PMID: 19910433; PMCID: PMC3575752.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    93. Safety and tolerability of putaminal AADC gene therapy for Parkinson disease. Neurology. 2009 Nov 17; 73(20):1662-9. Christine CW, Starr PA, Larson PS, Eberling JL, Jagust WJ, Hawkins RA, VanBrocklin HF, Wright JF, Bankiewicz KS, Aminoff MJ. PMID: 19828868; PMCID: PMC2839805.
      View in: PubMed   Mentions: 179     Fields:    Translation:HumansCTClinical Trials
    94. Introduction to special issue. Mol Imaging. 2009 Mar-Apr; 8(2):55. VanBrocklin HF. PMID: 19397850.
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    95. Development of an optimized activatable MMP-14 targeted SPECT imaging probe. Bioorg Med Chem. 2009 Jan 15; 17(2):653-9. Watkins GA, Jones EF, Scott Shell M, VanBrocklin HF, Pan MH, Hanrahan SM, Feng JJ, He J, Sounni NE, Dill KA, Contag CH, Coussens LM, Franc BL. PMID: 19109023; PMCID: PMC2639212.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    96. Advancing molecular imaging from the laboratory to everyday practice. J Nucl Med. 2008 Dec; 49(12):22N-23N. VanBrocklin HF. PMID: 19038993.
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    97. Bruce H. Hasegawa, PhD, 1951-2008. J Nucl Med. 2008 Sep; 49(9):37N-38N. Jones EF, Gould RG, VanBrocklin HF. PMID: 18765579.
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    98. Session 2: strategies for fast-track technological development and regulatory issues. J Nucl Med. 2008 Jun; 49(6):38N-39N. VanBrocklin H. PMID: 18511821.
      View in: PubMed   Mentions:    Fields:    Translation:PHPublic Health
    99. Molecular imaging update: advances in MI of the brain. J Nucl Med. 2007 May; 48(5):24N, 29N. VanBrocklin H, Herscovitch P. PMID: 17475948.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    100. Mitochondrial avid radioprobes. Preparation and evaluation of 7'(Z)-[125I]iodorotenone and 7'(Z)-[125I]iodorotenol. Nucl Med Biol. 2007 Jan; 34(1):109-16. VanBrocklin HF, Hanrahan SM, Enas JD, Nandanan E, O'Neil JP. PMID: 17210467; PMCID: PMC1852529.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    101. Anilinodialkoxyquinazolines: screening epidermal growth factor receptor tyrosine kinase inhibitors for potential tumor imaging probes. J Med Chem. 2005 Nov 17; 48(23):7445-56. VanBrocklin HF, Lim JK, Coffing SL, Hom DL, Negash K, Ono MY, Gilmore JL, Bryant I, Riese DJ. PMID: 16279804.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    102. A new precursor for the preparation of 6-[18F]Fluoro-L-m-tyrosine ([18F]FMT): efficient synthesis and comparison of radiolabeling. Appl Radiat Isot. 2004 Dec; 61(6):1289-94. VanBrocklin HF, Blagoev M, Hoepping A, O'Neil JP, Klose M, Schubiger PA, Ametamey S. PMID: 15388123.
      View in: PubMed   Mentions: 21     Fields:    
    103. Kinetic analysis of 18F-fluorodihydrorotenone as a deposited myocardial flow tracer: comparison to 201Tl. J Nucl Med. 2004 Nov; 45(11):1950-9. Marshall RC, Powers-Risius P, Reutter BW, O'Neil JP, La Belle M, Huesman RH, VanBrocklin HF. PMID: 15534068.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    104. Exemption of radiopharmaceuticals from <797>. J Nucl Med. 2004 Oct; 45(10):14N. Hung JC, VanBrocklin HF. PMID: 15551510.
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    105. No effect of age and estrogen on aromatic L- amino acid decarboxylase activity in rhesus monkey brain. Neurobiol Aging. 2002 May-Jun; 23(3):479-83. Eberling JL, Roberts JA, Taylor SE, VanBrocklin HF, O'Neil JP, Nordahl TE. PMID: 11959410.
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    106. Assessment of cancer-associated biomarkers by positron emission tomography: advances and challenges. Dis Markers. 2002; 18(5-6):211-47. Collier TL, Lecomte R, McCarthy TJ, Meikle S, Ruth TJ, Scopinaro F, Signore A, VanBrocklin H, van De Wiele C, Waterhouse RN. PMID: 14646039; PMCID: PMC3851410.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    107. A novel MPTP primate model of Parkinson's disease: neurochemical and clinical changes. Brain Res. 1998 Sep 14; 805(1-2):259-62. Eberling JL, Jagust WJ, Taylor S, Bringas J, Pivirotto P, VanBrocklin HF, Bankiewicz KS. PMID: 9733979.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    108. An in vivo microdialysis study of striatal 6-[18F]fluoro-L-m-tyrosine metabolism. Neurochem Res. 1998 Apr; 23(4):513-7. Jordan S, Bankiewicz KS, Eberling JL, VanBrocklin HF, O'Neil JP, Jagust WJ. PMID: 9566585.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    109. PET studies of functional compensation in a primate model of Parkinson's disease. Neuroreport. 1997 Aug 18; 8(12):2727-33. Eberling JL, Bankiewicz KS, Jordan S, VanBrocklin HF, Jagust WJ. PMID: 9295108.
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    110. 6-[18F]fluoro-L-m-tyrosine: metabolism, positron emission tomography kinetics, and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine lesions in primates. Brain Res. 1997 Mar 07; 750(1-2):264-76. Jordan S, Eberling JL, Bankiewicz KS, Rosenberg D, Coxson PG, VanBrocklin HF, O'Neil JP, Emborg ME, Jagust WJ. PMID: 9098552.
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    111. Iodine-123-5-iodo-6-nitroquipazine: SPECT radiotracer to image the serotonin transporter. J Nucl Med. 1996 Jul; 37(7):1207-14. Jagust WJ, Eberling JL, Biegon A, Taylor SE, VanBrocklin HF, Jordan S, Hanrahan SM, Roberts JA, Brennan KM, Mathis CA. PMID: 8965200.
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    112. PET studies of cerebral glucose metabolism in conscious rhesus macaques. Neurobiol Aging. 1995 Sep-Oct; 16(5):825-32. Eberling JL, Roberts JA, De Manincor DJ, Brennan KM, Hanrahan SM, Vanbrocklin HF, Roos MS, Jagust WJ. PMID: 8532117.
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    113. Synthesis and tissue biodistribution of [omega-11C]palmitic acid. A novel PET imaging agent for cardiac fatty acid metabolism. J Med Chem. 1994 Jul 22; 37(15):2481-5. Buckman BO, VanBrocklin HF, Dence CS, Bergmann SR, Welch MJ, Katzenellenbogen JA. PMID: 8057294.
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    114. The synthesis of 7 alpha-methyl-substituted estrogens labeled with fluorine-18: potential breast tumor imaging agents. Steroids. 1994 Jan; 59(1):34-45. VanBrocklin HF, Liu A, Welch MJ, O'Neil JP, Katzenellenbogen JA. PMID: 8140600.
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    115. In vivo imaging of the 5-hydroxytryptamine reuptake site in primate brain using single photon emission computed tomography and [123I]5-iodo-6-nitroquipazine. Eur J Pharmacol. 1993 Sep 28; 242(2):189-93. Jagust WJ, Eberling JL, Roberts JA, Brennan KM, Hanrahan SM, VanBrocklin H, Enas JD, Biegon A, Mathis CA. PMID: 8253114.
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    116. Titration of the in vivo uptake of 16 alpha-[18F]fluoroestradiol by target tissues in the rat: competition by tamoxifen, and implications for quantitating estrogen receptors in vivo and the use of animal models in receptor-binding radiopharmaceutical development. Nucl Med Biol. 1993 Aug; 20(6):735-45. Katzenellenbogen JA, Mathias CJ, VanBrocklin HF, Brodack JW, Welch MJ. PMID: 8401374.
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    117. 16 beta-([18F]fluoro)estrogens: systematic investigation of a new series of fluorine-18-labeled estrogens as potential imaging agents for estrogen-receptor-positive breast tumors. J Med Chem. 1993 May 28; 36(11):1619-29. VanBrocklin HF, Carlson KE, Katzenellenbogen JA, Welch MJ. PMID: 7684451.
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    118. Fluorine-18-labeled progestin ketals: synthesis and target tissue uptake selectivity of potential imaging agents for receptor-positive breast tumors. J Med Chem. 1993 Apr 30; 36(9):1120-7. Kochanny MJ, VanBrocklin HF, Kym PR, Carlson KE, O'Neil JP, Bonasera TA, Welch MJ, Katzenellenbogen JA. PMID: 8487253.
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    119. Synthesis, radiolabeling and tissue distribution of 11 beta-fluoroalkyl- and 11 beta-fluoroalkoxy-substituted estrogens: target tissue uptake selectivity and defluorination of a homologous series of fluorine-18-labeled estrogens. Nucl Med Biol. 1993 Jan; 20(1):31-47. French AN, Napolitano E, VanBrocklin HF, Hanson RN, Welch MJ, Katzenellenbogen JA. PMID: 8461878.
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    120. 16 beta-[18F]fluoromoxestrol: a potent, metabolically stable positron emission tomography imaging agent for estrogen receptor positive human breast tumors. Life Sci. 1993; 53(10):811-9. VanBrocklin HF, Rocque PA, Lee HV, Carlson KE, Katzenellenbogen JA, Welch MJ. PMID: 8355567.
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    121. Fluorine-substituted corticosteroids: synthesis and evaluation as potential receptor-based imaging agents for positron emission tomography of the brain. Int J Rad Appl Instrum B. 1992 May; 19(4):461-80. Pomper MG, Kochanny MJ, Thieme AM, Carlson KE, VanBrocklin HF, Mathias CJ, Welch MJ, Katzenellenbogen JA. PMID: 1526811.
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    122. Preparation and evaluation of 17-ethynyl-substituted 16 alpha-[18F]fluoroestradiols: selective receptor-based PET imaging agents. Int J Rad Appl Instrum B. 1992 Apr; 19(3):363-74. VanBrocklin HF, Pomper MG, Carlson KE, Welch MJ, Katzenellenbogen JA. PMID: 1629026.
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    123. 20-[18F]fluoromibolerone, a positron-emitting radiotracer for androgen receptors: synthesis and tissue distribution studies. J Nucl Med. 1991 Jan; 32(1):81-8. Liu AJ, Katzenellenbogen JA, VanBrocklin HF, Mathias CJ, Welch MJ. PMID: 1988641.
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    124. 11 beta-methoxy-, 11 beta-ethyl- and 17 alpha-ethynyl-substituted 16 alpha-fluoroestradiols: receptor-based imaging agents with enhanced uptake efficiency and selectivity. J Med Chem. 1990 Dec; 33(12):3143-55. Pomper MG, VanBrocklin H, Thieme AM, Thomas RD, Kiesewetter DO, Carlson KE, Mathias CJ, Welch MJ, Katzenellenbogen JA. PMID: 1701833.
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    125. Synthesis and tissue distribution of fluorine-18 labeled trifluorohexadecanoic acids. Considerations in the development of metabolically blocked myocardial imaging agents. Bioconjug Chem. 1990 Jul-Aug; 1(4):231-44. Pochapsky SS, VanBrocklin HF, Welch MJ, Katzenellenbogen JA. PMID: 2096916.
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    126. Binding of 16 alpha-[18F]fluoro-17 beta-estradiol to alphafetoprotein in Sprague-Dawley female rats affects blood levels. Int J Rad Appl Instrum B. 1990; 17(8):769-73. VanBrocklin HF, Brodack JW, Mathias CJ, Welch MJ, Katzenellenbogen JA, Keenan JF, Mizejewski GJ. PMID: 1706690.
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